He is currently the principal conductor of the Royal Liverpool Philharmonic Orchestra and principal conductor of the European Union Youth Orchestra. This year he will take on the positions of musical director of the Royal London Philharmonic Orchestra and artistic director of the Russian State Academic Symphony Orchestra.
He has been Artist of the Year at the 2017 Gramophone Awards, Male Artist of the Year at the 2010 BRIT Classical, and was named Doctor Honoris Causa by the Universities of Liverpool and Hope.
He has worked with orchestras such as the Berlin Philharmonic, the Leipzig Gewandhaus, the London Symphony and Philharmonic, the Philharmonia, the Accademia Nazionale of St. Cecilia, the St. Petersburg Philharmonic, the National Orchestra of France, the Czech Philharmonic, the NHK in Tokyo, the Sydney Orchestra, the Philadelphia Orchestra, the Los Angeles Philharmonic, Cleveland, San Francisco, Boston, Chicago, Montreal and St. Louis. He has also performed frequently at the BBC Proms.
In opera, he debuted in the Metropolitan Opera of New York with The Queen of Spades, in the 19/20 season.
His extensive discography includes Shostakovich's symphonic cycle for Naxos with the Royal Liverpool Philharmonic Orchestra and cycles of Scriabin's symphonies and Strauss's symphonic poems with the Oslo Philharmonic.